Adverse maternal and infant outcomes amongst mothers and infants in the Northern Territory, 1994-2014

Have the rates of adverse perinatal outcomes changed in Northern Territory mothers and infants following the introduction of the maternal vaccination in pregnancy policy, 1994-2014?

Pregnant women are targeted for influenza vaccine and pertussis (whooping cough) vaccines in pregnancy; however the uptake of the vaccines remains poor, particularly for influenza. There is limited data on outcomes following vaccine during pregnancy, and no data for Aboriginal and Torres Strait Islander mother-infant pairs. Given that Aboriginal and Torres Strait Islander mothers have double the maternal mortality rate (MMR) and higher rates of adverse perinatal outcomes compared with other Australian mothers, establishing the safety of maternal vaccines in pregnancy is important prior to implementing strategies to improve uptake particularly amongst this at risk group.

This project plans to conduct a retrospective cohort study analysing adverse maternal and infant perinatal outcomes amongst NT mothers and infants between 01 January 1994 and 31 December 2014. This data analysis project has an established study population.

The sample size is pre-determined at ~75,000 mother-infant pairs, of which ~35% identify as Aboriginal and or Torres Strait Islander. Results will be described in means, counts and proportions and the incidence of adverse birth outcomes will be expressed in ratio.

Contact: Lisa McHugh, Menzies School of Health Research (PhD student)

Email: lisa.mchugh@menzies.edu.au

Phone: 0418 200 553